PHARM-A-SPHERES

Sugar Spheres USP/NF, EP

Pharm-a-spheres are non-pareil seeds / neutral pellets of spherical form, composed of sucrose and corn starch. They are primarily used as inert cores in capsule and tablet formulations, particularly multi-particulate, sustained-release formulations. They form the base upon which a drug is coated, usually followed by a release-modifying polymer coating.

Pharm-a-spheres offer great mechanical strength, low friability and good flowability. Their high sphericity with a narrow particle size distribution allows precise calculation of drug loading quantity. Pharm-a-spheres range covers the whole spectrum of diameters from 90 μm - 2000 μm. Customized sizes of this product, to meet specific formulation needs are also possible.
Particle Size Ranges (mesh ASTM)

170 - 100

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Particle Size Ranges (μm)
90 - 150
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

100 - 80

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Particle Size Ranges (μm)
150 - 180
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

80 - 70

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Particle Size Ranges (μm)
180 - 212
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

70 - 60

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Particle Size Ranges (μm)
212 - 250
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

60 - 50

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Particle Size Ranges (μm)
250 - 300
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

50 - 45

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Particle Size Ranges (μm)
300 - 355
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

60 - 45

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Particle Size Ranges (μm)
250 - 355
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

60 - 40

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Particle Size Ranges (μm)
250 - 425
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

50 - 40

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Particle Size Ranges (μm)
300 - 425
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

45 – 40

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Particle Size Ranges (μm)
355 - 425
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

50 - 35

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Particle Size Ranges (μm)
300 - 500
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

45 - 35

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Particle Size Ranges (μm)
355 - 500
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

40 - 35

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Particle Size Ranges (μm)
425 - 500
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

35 - 30

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Particle Size Ranges (μm)
500 - 600
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

30 - 25

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Particle Size Ranges (μm)
600 - 710
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

25 - 20

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Particle Size Ranges (μm)
710 - 850
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

20 - 18

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Particle Size Ranges (μm)
850 - 1000
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

20 - 16

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Particle Size Ranges (μm)
850 - 1180
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

18 - 16

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Particle Size Ranges (μm)
1000 - 1180
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

16 - 14

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Particle Size Ranges (μm)
1180 - 1400
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

16 - 12

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Particle Size Ranges (μm)
1180 - 1700
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

14 - 12

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Particle Size Ranges (μm)
1400 - 1700
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
Particle Size Ranges (mesh ASTM)

12 - 10

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Particle Size Ranges (μm)
1700 - 2000
Applications
Drug-free cores for multi-particulate, sustained-release formulations
PDS
SDS
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