Products

SUGAR SPHERES
SUGAR SPHERES USP/NF, EP

Pharm-a-spheres are non-pareil seeds / neutral pellets of spherical form, composed of sucrose and corn starch. They are primarily used as inert cores in capsule and tablet formulations, particularly multi-particulate, sustained-release formulations. They form the base upon which a drug is coated, usually followed by a release-modifying polymer coating.

Pharm-a-spheres offer great mechanical strength, low friability and good flowability. Their high sphericity with a narrow particle size distribution allows precise calculation of drug loading quantity. Pharm-a-spheres’ range covers the whole spectrum of diameters from 90 μm - 2000 μm. Customized sizes of this product, to meet specific formulation needs are also possible.

Particle Size Range
(mesh ASTM)

Particle Size Range
(μm)

Applications

170 – 100

90 - 150

Drug-free cores for

multi-particulate, sustained-release formulations

80 - 100

150 - 180

70 - 80

180 - 212

60 - 70

212 - 250

50 - 60

250 - 300

45 - 50

300 - 355

45 - 60

250 - 355

40 - 60

250 - 425

40 - 50

300 - 425

40 - 45

355 - 425

35 - 50

300 - 500

35 - 45

355 - 500

35 - 40

425 - 500

30 - 35

500 - 600

25 - 30

600 - 710

20 - 25

710 - 850

18 - 20

850 - 1000

16 - 20

850 - 1180

16 - 18

1000 - 1180

14 - 16

1180 - 1400

12 - 16

1180 - 1700

12 - 14

1400 - 1700

10 - 12

1700 - 2000

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